Genetic Evaluation of CardiomyopathydA Heart Failure Society of America Practice Guideline

From the Card of Medicine, Miam rado Health Scien Program, Univers do; Howard Hug ter of Brigham & Massachusetts an Medicine, Houston Manuscript rec January 22, 2009; Reprint request School of Medicin 33101-5138. E-ma No conflicts of 1071-9164/$ s 2009 Elsevie doi:10.1016/j.ca Substantial progress has been made recently in understanding the genetic basis of cardiomyopathy. Cardiomyopathies with known genetic cause include hypertrophic (HCM), dilated (DCM), restrictive (RCM), arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) and left ventricular noncompaction (LVNC). HCM, DCM, and RCM have been recognized as distinct clinical entities for decades, whereas ARVD/C and LVNC are relative newcomers to the field. Hence the clinical and genetic knowledge for each cardiomyopathy varies, as do the recommendations and strength of evidence. (J Cardiac Fail 2009;15:83e97)