Shortening of cardiac action potential duration near an insulating boundary.
نویسندگان
چکیده
It is known, from both experiments and simulations, that cardiac action potentials are shortened near a non-conducting boundary. In the present paper, this effect is studied in a simple, two-current ionic model, with propagation restricted to a 1D fibre. An asymptotic approximation for the dependence of action potential duration on distance to the boundary is derived. This estimate agrees well with simulations.
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ورودعنوان ژورنال:
- Mathematical medicine and biology : a journal of the IMA
دوره 25 1 شماره
صفحات -
تاریخ انتشار 2008