Photodynamic therapy in the management of potentially malignant and malignant oral disorders
نویسندگان
چکیده
Photodynamic therapy (PDT) is a minimally-invasive surgical tool successfully targeting premalignant and malignant disorders in the head and neck, gastrointestinal tract, lungs and skin with greatly reduced morbidity and disfigurement. The technique is simple, can commonly be carried out in outpatient clinics, and is highly acceptable to patients. The role of photodynamic therapy in the management of oral potentially malignant disorders and early oral cancer is being discussed.
منابع مشابه
Fluorescence spectroscopy for the detection of potentially malignant disorders and squamous cell carcinoma of the oral cavity.
Oral cancer is a public health problem with relevant incidence in the world population. The affected patient usually presents advanced stage disease and the consequence of this delay is a reduction in survival rates. Given this, it is essential to detect oral cancer at early stages. Fluorescence spectroscopy is a non-invasive diagnostic tool that can improve cancer detection in real time. It is...
متن کاملThe role of photodynamic therapy in the management of oral dysplasia
Materials and methods In this prospective study, a total of 147 consecutive patients with potentially malignant disorders were treated with surface illumination PDT, using 5-ALA or mTHPC as the photosensitiser. The average age was 53±8.9 years. Patients’ recovery was uneventful and no complications reported. Comparisons with the clinical and histopathological features and rate of recurrence as ...
متن کاملRole of Photodynamic Therapy in the Treatment of Oral Cancer: A Review
Oral cancer is a major public health problem worldwide and is among the ten most common cancers. Despite the advances in research and treatment, oral cancer is still one of the major challenges in medical science. Common treatments for this cancer include surgery, radiotherapy, and chemotherapy, as well as adjuvant photodynamic therapy (PDT). The aim of this study was to evaluate oral cancer an...
متن کاملA Review of Oral Submucousal Fibrosis, Related Factors, Prognosis and New Therapeutic Approaches
Abstract BACKGROUNackground and AIMD & AIM: Oral Submucous Fibrosis (OSF) is an oral premalignant condition with highest premalignant potential among oral precancerous lesions which characterized with inflammation and progressive fibrosis of submucosal oral tissues (cause to significant irreversible rigidity and trismus). During the years, many classification systems have been propo...
متن کاملبررسی شیوع تغییرات بدخیمی در لیکن پلان دهانی در دو مرکز اصلی در شهر شیراز از سال 1385 الی 1388
Background and purpose: Ôral lichen planus (ÔLP), a common disease reported to be a premalignant lesion in some studies, may potentially lead to the development of oral squamous cell carcinoma. This study aims to investigate the prevalence of malignant transformation in patients with ÔLP. Materials and methods: Ïn this retrospective study, 386 patients diagnosed with ÔLP based on the criteri...
متن کامل