WESTERN BLOT DETERMINATION OF IgG AVIDITY IN PRIMARY AND SECONDARY SYPHILIS

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چکیده

In this study, we analysed IgG avidity to p 15.5 kD, p 17 kD and p 47 kD antigens by a new avidity assay termed avidity western blot. The determination was performed in two groups. Group I consisted of 27 patients with primary and secondary syphilis and group II comprised 10 subjects with latent syphilis. We found that low avidity antibodies were directed against the p 17 kD and p 47 kD antigens in group I and against the p 47 kD antigen in group II. No low-avidity IgG antibodies were detected by ELISA, a routine method for avidity assessment.

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تاریخ انتشار 2002