tomosis (subtotal or segmental colectomy) with or without intraoperative colonic irrigation and colonic stenting (7). Emergency surgery for acute colonic obstruction carries a significant risk of mortality and morbidity: The 30-day postoperative mortality rate is 7.6%, with anastomotic dehis-
نویسندگان
چکیده
The aim of the present study was to investigate the shortand long-term outcomes of patients undergoing second-look surgery following Hartmann's procedure for obstructive left-sided colorectal cancer (LSCC). All patients included in the present study had undergone radical surgery with Hartmann's procedure for obstructive LSCC. Adjuvant chemotherapy was recommended for all patients, and patients with no signs of recurrence following six months of surveillance were planned to undergo second-look surgery. The aim of second-look surgery was early detection of local recurrence and determination of the efficacy of laparoscopic Hartmann procedure reversal. A total of 15 patients with locally advanced colorectal cancer were included in the study. Three patients exhibited peritoneal dissemination at the time of laparoscopic Hartmann procedure reversal and underwent partial peritonectomy. Following adjuvant chemotherapy treatment, laparoscopic Hartmann procedure reversal was performed in all patients. However, two patients underwent colo-anal anastomosis, and two patients underwent right-sided colon or ileum reconstruction. Regarding the oncological outcomes, two of three patients in whom peritoneal dissemination was identified during laparoscopic Hartmann procedure reversal were eventually in remission following the initial surgery and the second-look surgery with partial peritonectomy. Favorable long-term outcomes were observed in 12/15 patients due to no recurrence, which may be due to the surgical techniques used and the timing of the second-look surgery following Hartmann's procedure for the treatment of obstructive LSCC. Introduction Approximately 15-20% of patients with left-sided colorectal cancer (LSCC) present with symptoms of acute obstruction (1-4). Patients with obstructive LSCC require emergency surgery, and a high rate of surgical complications and poor prognosis have been reported in these cases (5,6). Emergency management of acute left-sided colonic obstruction remains controversial and at present several treatments options exist, including simple colostomy, primary resection with end colostomy (Hartmann's procedure), one-stage resection anastomosis (subtotal or segmental colectomy) with or without intraoperative colonic irrigation and colonic stenting (7). Emergency surgery for acute colonic obstruction carries a significant risk of mortality and morbidity: The 30-day postoperative mortality rate is 7.6%, with anastomotic dehiscence occurring in 4.9% of cases (2). Thus, 46% of patients require stoma treatment that is permanent (2). To reduce the risk of complications, laparoscopic Hartmann procedure reversal is commonly used for LSCC, since it is considered to reduce the morbidity caused by anastomotic dehiscence (8). However, re-establishing intestinal continuity during laparoscopic Hartmann procedure reversal for LSCC remains a major problem and it carries a serious risk of significant morbidity, with reported anastomotic leak rates of 4-16% and a mortality rate of up to 10% (9,10). Stoma closure is difficult, as colorectal malignancies require segmental colostomy with lymph node dissection, which results in a high rate of dense adhesions (10). Additionally, LSCC is associated with a poor prognosis due to the large size and high frequency of gastrointestinal strictures (11). In addition, certain cases exhibit peritoneal dissemination, which exposes the cancer cells to the serosa (12). Thus, it is important to consider these surgical and oncological factors when planning a laparoscopic Hartmann procedure reversal for LSCC, since these difficulties may prevent the success of this surgical procedure, which was previously reported to be ~20% for LSCC (11). In the present study, second-look surgery was performed in patients with no signs of recurrence following six months of surveillance subsequent to Hartmann's procedure. The present study aimed to determine the efficacy of laparoscopic Hartmann procedure reversal and to assess local recurrence. The aim of the present study was to investigate the shortand Second-look surgery following Hartmann's procedure for obstructive left-sided colorectal cancer NAOHITO BEPPU1, FUMIHIKO KIMURA1, NAGAHIDE MATSUBARA2, MASASHI NODA2, NAOHIRO TOMITA2, HIDENORI YANAGI1 and NAOKI YAMANAKA1 1Department of Surgery, Meiwa Hospital, Nishinomiya, Hyogo 663-8186; 2Department of Surgery, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan Received December 9, 2014; Accepted January 18, 2016 DOI: 10.3892/ol.2016.5084 Correspondence to: Dr Naohito Beppu, Department of Surgery, Meiwa Hospital, 4-31 Agenaruo-cho, Nishinomiya, Hyogo 663-8186,
منابع مشابه
Subtotal colectomy for malignant left-sided colon obstruction is associated with a lower anastomotic leak rate than segmental colectomy.
AIM To compare subtotal colectomy to segmental colectomy for malignant left-sided colonic obstruction. PATIENTS AND METHODS Obstruction was defined by failure to trespass a colonic stenosis during endoscopy, by truncation of the contrast column during contrast enema, by severe colonic dilatation (cecum >10 cm, transverse colon >8 cm, descending colon >6 cm) or by serosal tears. From 53 consec...
متن کاملGuidelines in the management of obstructing cancer of the left colon : consensus conference of the world society of emergency surgery (WSES) and peritoneum and surgery (PnS) society
Background: Obstructive left colon carcinoma (OLCC) is a challenging matter in terms of obstruction release as well of oncological issues. Several options are available and no guidelines are established. The paper aims to generate evidenced based recommendations on management of OLCC. Methods: The PubMed and Cochrane Library databases were queried for publications focusing on OLCC published pri...
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Intestinal obstruction is a significant disease specially in patients with previous surgery. Patients symptoms and signs usually are abdominal pain, vomiting, abdominal distention and obstipation. Adhesion bands secondary to previous abdominal surgery is the most common cause of small bowel obstruction and in USA up to 70% of small bowel obstruction is caused by adhesions. In our study adhesion...
متن کاملGuidelenines in the management of obstructing cancer of the left colon: consensus conference of the world society of emergency surgery (WSES) and peritoneum and surgery (PnS) society
BACKGROUND Obstructive left colon carcinoma (OLCC) is a challenging matter in terms of obstruction release as well of oncological issues. Several options are available and no guidelines are established. The paper aims to generate evidenced based recommendations on management of OLCC. METHODS The PubMed and Cochrane Library databases were queried for publications focusing on OLCC published pri...
متن کاملSurgical Treatment of Obstructed Left-Sided Colorectal Cancer Patients
Colorectal cancer is the single most common cause of large intestinal obstruction. Approximately 2% to 5% of colorectal cancer patients have an obstruction. Cancer arising in the rectum or left colon is more likely to obstruct than cancer arising in the proximal colon. Acute colonic obstruction produces a dilated bowel with a large amount of fecal loading that is proximal to the blockage and is...
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