Tetrafibricin, a novel fibrinogen receptor antagonist. II. Structural elucidation.

نویسندگان

  • T Kamiyama
  • Y Itezono
  • T Umino
  • T Satoh
  • N Nakayama
  • K Yokose
چکیده

The structure of tetrafibricin, a novel and potent fibrinogen receptor antagonist isolated from the culture broth of Streptomyces neyagawaensis NR0577, was determined. Tetrafibricin has a unique structure containing primary amine, conjugated tetraenoic acid, and polyhydroxy functionalities that is biosynthetically related to the polyene macrolide antibiotics.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 46 7  شماره 

صفحات  -

تاریخ انتشار 1993