A deletion variant of the alpha2b-adrenoceptor is related to emotional memory in Europeans and Africans.
نویسندگان
چکیده
Emotionally arousing events are recalled better than neutral events. This phenomenon, which helps us to remember important and potentially vital information, depends on the activation of noradrenergic transmission in the brain. Here we show that a deletion variant of ADRA2B, the gene encoding the alpha2b-adrenergic receptor, is related to enhanced emotional memory in healthy Swiss subjects and in survivors of the Rwandan civil war who experienced highly aversive emotional situations.
منابع مشابه
A deletion variant of the a2b-adrenoceptor is related to emotional memory in Europeans and Africans
Emotionally arousing events are recalled better than neutral events. This phenomenon, which helps us to remember important and potentially vital information, depends on the activation of noradrenergic transmission in the brain. Here we show that a deletion variant of ADRA2B, the gene encoding the a2b-adrenergic receptor, is related to enhanced emotional memory in healthy Swiss subjects and in s...
متن کاملA genetic variation of the noradrenergic system is related to differential amygdala activation during encoding of emotional memories.
Emotionally arousing events are typically well remembered, but there is a large interindividual variability for this phenomenon. We have recently shown that a functional deletion variant of ADRA2B, the gene encoding the alpha2b-adrenergic receptor, is related to enhanced emotional memory in healthy humans and enhanced traumatic memory in war victims. Here, we investigated the neural mechanisms ...
متن کاملDeletion variant in the ADRA2B gene increases coupling between emotional responses at encoding and later retrieval of emotional memories.
A deletion variant of the ADRA2B gene that codes for the α2b adrenoceptor has been linked to greater susceptibility to traumatic memory as well as attentional biases in perceptual encoding of negatively valenced stimuli. The goal of the present study was to examine whether emotional enhancements of memory associated with the ADRA2B deletion variant were predicted by encoding, as indexed by the ...
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BACKGROUND An insertion/deletion polymorphism in the alpha2B-adrenoceptor (AR) has been associated with the risk for acute myocardial infarction (AMI) and sudden cardiac death. In this study we tested whether this polymorphism is associated with the risk for AMI among members of families with type 2 diabetes. METHODS 154 subjects with a history of AMI were matched for age and sex with one of ...
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ورودعنوان ژورنال:
- Nature neuroscience
دوره 10 9 شماره
صفحات -
تاریخ انتشار 2007