Dynamic combinatorial chemistry with diselenides and disulfides in water.

Synthesis of disulfides and diselenides by copper-catalyzed coupling reactions in water.

A simple and efficient protocol for copper-catalyzed coupling reactions between aryl halides and elemental sulfur or selenium has been developed. A variety of disulfides and diselenides can be obtained in moderate to excellent yields up to 96%.

Convenient method for the synthesis of symmetrical disulfides using 1-butyl- 3-methylimidazolium hydroxide in water

Phase-transfer dynamic combinatorial chemistry.

A two-phase approach to dynamic combinatorial chemistry is described using disulfide exchange chemistry; the use of two phases significantly increases the possibilities and the scope of dynamic combinatorial chemistry by facilitating the combination of otherwise incompatible building blocks.

Palladium-catalyzed addition of disulfides and diselenides to alkynes under solvent free conditions.

An efficient methodology was developed for performing palladium-catalyzed E-E (E = S, Se) bond addition to alkynes under solvent free conditions. Compared to reaction in solvent significant enhancement of reaction rate, improved efficiency and remarkable catalyst stability were observed under solvent free conditions. The addition reactions were carried out with high stereoselectivity and yields...

Efficient silver-catalyzed direct sulfenylation and selenylation of rich arenes.

An efficient protocol for silver/copper-cocatalyzed direct sulfenylation and selenylation of arenes with aryl disulfides and diselenides has been developed. This strategy exhibits excellent functional group tolerance and high regioselectivity. Mono sulfenylation and selenylation products can be exclusively achieved. This reaction provides a simple and practical route to the preparation of aryl ...