Cytokine Production by the Murine after Exposure to Lactobacilli MacrophageCeilLine J 774 . 1 JseA
نویسنده
چکیده
ity to induce the murine macrephage-like cell line J774.1 to secrete cytokines. Some ef the bacteria tested induce the preduction of interleukin(IL) 6, IL-12, and tumor necrosis factor a (TNF-a) by J774.1 cells. Seyen strains also induced the produetion of IL-10. However, ne IL1fi was produced. LactobaciUdes acidophiltts TMC 0356 significantly induced the production of more IL-6, IL-10, IL-12, and TNF-a than the other bacteria tested (p<O.OOOI; ANOVA). These results suggest that lactobacilli can activate macrophages te secrete both inflammatory and anti-i"fiammatory cytokines. Selected strains might be used to bring about pro or antiinflammatory immune reactions.
منابع مشابه
Cytokine Production by the Murine after Exposure to Lactobacilli MacrophageCeilLine J 774 .
ity to induce the murine macrephage-like cell line J774.1 to secrete cytokines. Some ef the bacteria tested induce the preduction of interleukin(IL) 6, IL-12, and tumor necrosis factor a (TNF-a) by J774.1 cells. Seyen strains also induced the produetion of IL-10. However, ne IL1fi was produced. LactobaciUdes acidophiltts TMC 0356 significantly induced the production of more IL-6, IL-10, IL-12, ...
متن کاملT Helper 2 Cytokine Analysis of Bronchoalveolar Lavage in the Murine Model of Allergic Broncho Pulmonary Aspergillosis
Background and Aims: Aspergillus fumigatus is a sporadic fungus that causes different infections and allergies in immunocompromised patients. The allergic disease caused by this fungus is called allergic bronchopulmonary aspergillosis (ABPA). ABPA is considred important in atopic and immunocompromised individuals, which can result in inflammation and epithelial damage. Therefore, the aim of thi...
متن کاملAbsolute quantification of murine interleukine-4, interleukine- 10 and interferon-γ gene transcripts using Real Time PCR
The study of cytokines gene expression is quite important in various conditions of health and disease for the evaluation of clinical responses to new vaccination approaches. An absolute quantification is based on a calibration curve and production of standard controls to achieve more reliable results than in relative system. In this study we attempted to construct standard controls to evaluate ...
متن کاملSurface Markers in Murine Dendritic Cells Expression of Cytokines and Maturation Lactobacilli Differentially Modulate
متن کامل
Fermentative Lactic Acid Production by Lactobacilli: Moser and Gompertz Kinetic Models
Lactic acid production in a batch submerged fermentation process by five Lactobacilli: bulgaricus, casei, lactis, delbrueckii and fermentum in lactose fortified whey culture were investigated. Kinetic behavior of Lactobacilli growth rate and lactose utilization was studied based on the Moser and Gompertz kinetic models. Trendline tool in Excel software was applied for fitness assessment of the ...
متن کامل