Hypertrophic Scars and KeloidsFA Review of Their Pathophysiology, Risk Factors, and Therapeutic Management
نویسنده
چکیده
Hypertrophic scars and keloids are a problem that mainly dermatologists and plastic surgeons encounter. Especially in the head and neck region, these lesions are conspicuous and not easy for patients to conceal. Patients typically present with cosmetic concerns, although hypertrophic scars and keloids can also cause pruritus, pain, or pressure. This article reviews various treatment modalities for aberrant wound healing and the updated findings of molecular scar biology.
منابع مشابه
Hypertrophic scars and keloids--a review of their pathophysiology, risk factors, and therapeutic management.
BACKGROUND Hypertrophic scars and keloids result from an abnormal fibrous wound healing process in which tissue repair and regeneration-regulating mechanism control is lost. These abnormal fibrous growths present a major therapeutic dilemma and challenge to the plastic surgeon because they are disfiguring and frequently recur. OBJECTIVE To provide updated clinical and experimental information...
متن کاملHypertrophic scars and Keloids
The available treatment modalities for hypertrophic scars and keloids have very little success. Surgical treatment of these lesions without adjuvant therapy is also associated with high recurrence rate. Hypertrophic scars and keloids are the results of a series of cellular and molecular changes which their identification can guide us toward new treatment modalities which may decrease the ...
متن کاملHypertrophic scars and Keloids
The available treatment modalities for hypertrophic scars and keloids have very little success. Surgical treatment of these lesions without adjuvant therapy is also associated with high recurrence rate. Hypertrophic scars and keloids are the results of a series of cellular and molecular changes which their identification can guide us toward new treatment modalities which may decrease the ...
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Background: Microneedling is recently used to treat skin scars mostly atrophic scars; however, there are limited data about its effectiveness on hypertrophic burn scars. Carbon dioxide (CO2) laser is an effective method for the treatment of burn scars. Here, we aim to compare the efficacy of microneedling to CO2 laser in the treatment of hypertrophic burn scars in a randomized clinical trial. M...
متن کاملNew insights into the prevention and treatment strategies for hypertrophic scars and keloids
Hypertrophic scars and keloids are fibrosis abnormalities associated with the accumulation of collagen and extra cellular matrix components. These scars are caused by abnormal wound healing, which may occur after skin injuries caused by surgery, trauma, burns, etc. and may have a large impact on the patients’ quality of life. Hypertrophic scars and colloids in addition to aesthetic problems can...
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