Disequilibrium in distribution of resistance mutations among Mycobacterium tuberculosis Beijing and non-Beijing strains isolated from patients in Germany.

نویسندگان

  • Doris Hillemann
  • Tanja Kubica
  • Sabine Rüsch-Gerdes
  • Stefan Niemann
چکیده

Genotypic analysis of 103 multidrug-resistant Mycobacterium tuberculosis strains isolated in Germany in 2001 revealed that mutations in codon 531 (75.7%) of the rpoB gene and codon 315 (88.4%) of the katG gene are most frequent. Beijing genotype strains (60.2% of all isolates) displayed a different distribution of resistance mutations than non-Beijing strains.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 49 3  شماره 

صفحات  -

تاریخ انتشار 2005