Lethal Streptococcus pyogenes post - partum sepsis : Molecular 1 analysis of an outbreak
نویسندگان
چکیده
Claire E Turner, Matthew Dryden, Matthew T G Holden, Frances J Davies, Richard A 3 Lawrenson, Leili Farzaneh, Stephen D Bentley, Androulla Efstratiou, Shiranee 4 Sriskandan. 5 6 Infectious Diseases & Immunity, Imperial College London, Hammersmith Hospital, Du 7 Cane Road, London, W12 0NN, UK, Royal Hampshire County Hospital, Winchester, 8 Hampshire, SO22 5DG UK, Pathogen Genomics, The Wellcome Trust Sanger Institute, 9 Hinxton, Cambridge, CB10 1SA UK, Microbiology Reference Services Division, Public 10 Health England (formerly Health Protection Agency), Colindale, London, NW8 5EQ, UK. 11 12 Author for correspondence: 13 Prof. Shiranee Sriskandan FRCP PhD 14 The National Centre for Infection Prevention and Management 15 Department of Infectious Diseases & Immunity 16 Imperial College Faculty of Medicine 17 Hammersmith Hospital, Du Cane Rd, London W12 0NN 18 Tel +44 (0)208 383 3135/3243; Fax +44 (0)208 383 3394 19 [email protected] 20 21 Running title: S. pyogenes post-partum sepsis 22 23 Copyright © 2013, American Society for Microbiology. All Rights Reserved. J. Clin. Microbiol. doi:10.1128/JCM.00679-13 JCM Accepts, published online ahead of print on 24 April 2013
منابع مشابه
Molecular Analysis of an Outbreak of Lethal Postpartum Sepsis Caused by Streptococcus pyogenes
Sepsis is now the leading direct cause of maternal death in the United Kingdom, and Streptococcus pyogenes is the leading pathogen. We combined conventional and genomic analyses to define the duration and scale of a lethal outbreak. Two postpartum deaths caused by S. pyogenes occurred within 24 h; one was characterized by bacteremia and shock and the other by hemorrhagic pneumonia. The women ga...
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