Trace alignment and some of its applications
نویسنده
چکیده
MOTIVATION Extra useful information can be extracted from a DNA chromatogram trace, over that contained in the base-called DNA sequence. Many sequencing applications can benefit from examination of these traces. RESULTS An algorithm, based on dynamic programming, for aligning a DNA chromatogram to a DNA sequence is described and implemented. Its applications to vector clipping, EST alignment and mutation detection are discussed.
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ورودعنوان ژورنال:
- Bioinformatics
دوره 14 1 شماره
صفحات -
تاریخ انتشار 1998