FIRE AND ICE: The quest for the perfect modality in atrial fibrillation ablation
نویسندگان
چکیده
Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. Catheter ablation of atrial fibrillation plays an important role in the management of AF. Radiofrequency ablation is widely used in practice all over the world. Cryoablation has emerged as an alternative method for AF ablation. The FIRE and ICE trial was a non inferiority, multicentre, randomized trial that compared between the two modalities and proved cryoablation to be non inferior to radiofrequency in terms of efficacy and safety. However, the rate of AF recurrence was markedly high in both arms of the study.
منابع مشابه
The Impact of Cryoballoon Versus Radiofrequency Ablation for Paroxysmal Atrial Fibrillation on Healthcare Utilization and Costs: An Economic Analysis From the FIRE AND ICE Trial
BACKGROUND This study sought to assess payer costs following cryoballoon or radiofrequency current (RFC) catheter ablation of paroxysmal atrial fibrillation in the randomized FIRE AND ICE trial. METHODS AND RESULTS A trial period analysis of healthcare costs evaluated the impact of ablation modality (cryoballoon versus RFC) on differences in resource use and associated payer costs. Analyses w...
متن کاملCryoballoon or radiofrequency ablation for symptomatic paroxysmal atrial fibrillation: reintervention, rehospitalization, and quality-of-life outcomes in the FIRE AND ICE trial
AIMS The primary safety and efficacy endpoints of the randomized FIRE AND ICE trial have recently demonstrated non-inferiority of cryoballoon vs. radiofrequency current (RFC) catheter ablation in patients with drug-refractory symptomatic paroxysmal atrial fibrillation (AF). The aim of the current study was to assess outcome parameters that are important for the daily clinical management of pati...
متن کاملCryoballoon or Radiofrequency Ablation for Paroxysmal Atrial Fibrillation.
BACKGROUND Current guidelines recommend pulmonary-vein isolation by means of catheter ablation as treatment for drug-refractory paroxysmal atrial fibrillation. Radiofrequency ablation is the most common method, and cryoballoon ablation is the second most frequently used technology. METHODS We conducted a multicenter, randomized trial to determine whether cryoballoon ablation was noninferior t...
متن کاملBiophysics of the second-generation cryoballoon: cryobiology of the big freeze.
C urrent guidelines recommend antral isolation of the pulmonary veins (PV) as the cornerstone of atrial fibrillation ablation. 1 Although conventional radiofrequency energy has traditionally been used with a point-by-point approach, cryo-ablation has emerged as a viable alternative to radiofrequency energy. The clinical success of cryoablation has been driven by the introduction of the cryoball...
متن کاملAF ablation: Single shot multielectrode or multishot single electrode?
There is no doubt that catheter ablation is established as an important tool in the armoury used in the management of symptomatic, drug-resistant atrial fibrillation [1]. Effective pulmonary vein isolation continues to be the main foundation of this approach [2]. Complete isolation of the pulmonary veins is associated with fewer atrial fibrillation recurrences when compared with incomplete lesi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
دوره 2016 شماره
صفحات -
تاریخ انتشار 2016