A systematic review of diagnostic procedures to detect midgut neuroendocrine tumors.
نویسندگان
چکیده
The aim of this work was to assess the diagnostic yield of some clinical diagnostic procedures utilized to establish a diagnosis of midgut neuroendocrine tumors (NETs). Medical databases published between 1982 and 2007 were analyzed. Seventeen observational studies, including 629 patients, met the inclusion criteria. Urinary 5-HIAA is the first test to prescribe in patients with flushing or persistent, unexplained diarrhea. Abdominal CT scan and OctreoScan should be prescribed whenever NET is suspected.
منابع مشابه
Current Diagnostic Status of Pheochromocytomaand Future Perspective: A Mini Review
Pheochromocytomas (PCCs) are rare neuroendocrine tumors. The current diagnostic tools are based on biochemistry and histopathology results, but heterogeneity of diagnostic markers, signs and symptoms of PCCs bring a lot of difficulties for these two current methods. Unfortunately microscopic understanding of PCCs is not adequate for its confident prognosis and management. There are data linking...
متن کاملSATB2 is a sensitive marker for lower gastrointestinal well-differentiated neuroendocrine tumors.
Special AT-rich sequence binding protein-2 (SATB2) is selectively expressed in the lower gastrointestinal tract mucosa and has been identified as a sensitive marker for colorectal adenocarcinomas. The goal of this study was to investigate the expression of SATB2 in well-differentiated neuroendocrine tumors to explore its potential as a diagnostic marker for hindgut well-differentiated neuroendo...
متن کاملPrimary midgut carcinoid, a rare cause of paraneoplastic limbic encephalitis: a case report.
A 60-year-old male presented with an unexplained seizure whose aetiology could not be demonstrated. After 8 weeks, patient on evaluation for abdominal pain was detected to have primary midgut carcinoid with nodal and hepatic metastasis. Patient underwent cytoreductive surgery and metastatectomy with successful outcome. The case is being presented for its rarity and the need to recognize the par...
متن کاملEvaluation of Neuroendocrine and Proliferative Markers in Prostatic Adenocarcinomas
Background: Certain marker studies have practical importance in the biology of prostate cancer. The purpose of this study was to determine whether the quantification of certain neuroendocrine and proliferative markers obtained during transurethral resection or prostatectomy, would help in the prognostic evaluation of prostatic adenocarcinomas. Methods: The present study was performed on samples...
متن کاملQuality of life, resource utilisation and health economics assessment in advanced neuroendocrine tumours: a systematic review
Neuroendocrine tumours (NET) are often diagnosed at an advanced stage when the prognosis is poor for patients, who often experience diminished quality of life (QoL). As new treatments for NET become available, it is important to characterise the associated outcomes, costs and QoL. A comprehensive search was performed to systematically review available data in advanced NET regarding cost of illn...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of surgical oncology
دوره 102 7 شماره
صفحات -
تاریخ انتشار 2010