Validation of dynamic three-dimensional whole heart magnetic resonance myocardial perfusion imaging at 3.0 Tesla against fractional flow reserve for the detection of flow-limiting coronary heart disease
نویسندگان
چکیده
We demonstrate the feasibility of 3D myocardial perfusion CMR at 3 Tesla against fractional flow reserve (FFR) in 53 patients for the detection of flow-limiting coronary artery disease and show good agreement between the techniques. This technique shows excellent diagnostic sensitivity and specificity and may offer an alternative method of detecting ischaemia for the purpose of guiding revascularisation and risk stratification.
منابع مشابه
Whole-heart dynamic three-dimensional magnetic resonance perfusion imaging for the detection of coronary artery disease defined by fractional flow reserve: determination of volumetric myocardial ischaemic burden and coronary lesion location.
AIMS Dynamic three-dimensional-cardiac magnetic resonance (3D-CMR) perfusion proved highly diagnostic for the detection of angiographically defined coronary artery disease (CAD) and has been used to assess the efficacy of coronary stenting procedures. The present study aimed to relate significant coronary lesions as assessed by fractional flow reserve (FFR) to the volume of myocardial hypoenhan...
متن کاملValidation of dynamic three-dimensional whole heart magnetic resonance myocardial perfusion imaging at 3.0 Tesla against the duke jeopardy score to assess myocardium at risk
We demonstrate the feasibility of 3D myocardial perfusion CMR at 3 Tesla against invasive measures of myocardium at risk and ischaemic burden (Duke Jeopardy Score) in fifty-three patients for the detection of flowlimiting coronary artery disease and show good agrement between the techniques (Pearson r=0.82). This led to the novel use of this technique as a non-invasive method of detecting ischa...
متن کاملValidation of dynamic three-dimensional whole heart magnetic resonance myocardial perfusion imaging against single photon emission computed tomography for the detection of functionally significant coronary heart disease
We demonstrate the feasibility of 3D myocardial perfusion CMR at 3 Tesla against single photon emission computer tomography for the detection and estimate of ischaemic burden and show good agreement between the techniques. This novel technique shows promising use of this method in a small cohort of patients to estimate ischaemic burden for purpose of risk stratification of patients with known o...
متن کاملValidation of dynamic 3-dimensional whole heart magnetic resonance myocardial perfusion imaging against fractional flow reserve for the detection of significant coronary artery disease.
OBJECTIVES The goal of this study was to determine the diagnostic accuracy of dynamic 3-dimensional (3D) whole heart myocardial perfusion cardiovascular magnetic resonance (CMR) against invasively determined fractional flow reserve (FFR) and to establish the correlation between myocardium at risk defined by using the invasive Duke Jeopardy Score (DJS) and noninvasive 3D whole heart myocardial p...
متن کاملMulticenter evaluation of dynamic three-dimensional whole-heart myocardial perfusion imaging for the detection of coronary artery disease defined by fractional flow reserve
Background Cardiac magnetic resonance (CMR) perfusion imaging yields high diagnostic accuracy for the detection of coronary artery disease (CAD) [1]. However, standard 2D multislice CMR perfusion techniques only provide limited coverage and hence prohibit computation of myocardial ischemic burden. Recently, two single-center 3D CMR perfusion studies have proven highly diagnostic for the detecti...
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