Dose for Proton Irradiation
نویسنده
چکیده
With the increase in the amount of time spent EVA that is necessary to complete the construction and subsequent maintenance of ISS, it will become increasingly important for ground support personnel to accurately characterize the radiation exposures incurred by EVA crewmembers. Since exposure measurements cannot be taken within the organs of interest, it is necessary to estimate these exposures by calculation. To validate the methods and tools used to develop these estimates, it is necessary to model experiments performed in a controlled environment. This work is such an effort. A human phantom was outfitted with detector equipment and then placed in American EMU and Orlan-M EVA space suits. The suited phantom was irradiated at the LLUPTF with proton beams of known energies. Absorbed dose measurements were made by the spaceflight operational dosimetrist from JSC at multiple sites in the skin, eye, brain, stomach, and small intestine locations in the phantom. These exposures are then modeled using the BRYNTRN radiation transport code developed at the NASA Langley Research Center (Wilson et al., 1989), and the CAM (computerized anatomical male) human geometry model of Billings and Yucker (1 973). Comparisons of absorbed dose calculations with measurements show excellent agreement. This suggests that there is reason to be confident in the ability of both the transport code and the human body model to estimate proton exposure in ground-based laboratory experiments.
منابع مشابه
Comparison of Different Model Predictions on RBE in the Proton Therapy Technique Using the GATE Code
Recently, proton therapy is used as one of the effective methods for treating various types of cancer in clinical treatment. An appropriate formalism to obtain relative biological effectiveness values for treatment planning studies is needed in this hadrontherapy technique. Hereby, the quantity of biological dose, instead of using the physical doses, is introduced to evaluate the biological eff...
متن کاملInvestigation of tumor motion influence on applied dose distribution in conventional proton therapy vs. IMPT a 4D Monte Carlo simulation study
Background: in radiation treatment of moving targets located in thorax region of patient body, the delivered dose does not match with the planned treatment, resulting in some over and under dosage in the tumor volume, as a function of motion magnitude and frequency. Several efforts have been done to investigate the target motion effects on dose distribution in the target and surrounding normal ...
متن کاملTechnique for sparing previously irradiated critical normal structures in salvage proton craniospinal irradiation
BACKGROUND Cranial reirradiation is clinically appropriate in some cases but cumulative radiation dose to critical normal structures remains a practical concern. The authors developed a simple technique in 3D conformal proton craniospinal irradiation (CSI) to block organs at risk (OAR) while minimizing underdosing of adjacent target brain tissue. METHODS Two clinical cases illustrate the use ...
متن کاملComponent irradiation studies with the 72 MeV OPTIS proton beam : Low dose - rate irradiation of UHF 1 X transistors
Having to design electronics for high-energy physics experiment such as the Electromagnetic CALorimer (ECAL) of the Compact Muon Solenoid (CMS) experiment leads to the study of components under irradiation. We are designing a radhard readout system. This paper will present the facility we are using to study and validate the radiation hardness of our system. This is a proton beam located at the ...
متن کاملANALYSIS OF A CLAD TUNGSTEN TARGET AFTER IRRADIATION IN AN 800 MeV PROTON BEAM
For the Accelerator Production of Tritium (APT) and the Accelerator Driven Transmutation Facility (ADTF), tungsten is being proposed as a target material to produce neutrons. Previous work showed that the mechanical properties of tungsten are degraded from irradiation in a neutron flux but little work had been performed on the irradiation of tungsten in a high energy proton beam. In this study,...
متن کاملOptimized enzymatic dual functions of PaPrx protein by proton irradiation
We investigated the effects of proton irradiation on the function and structure of the Pseudomonas aeruginosa peroxiredoxin (PaPrx). Polyacrylamide gel demonstrated that PaPrx proteins exposed to proton irradiation at several doses exhibited simultaneous formation of high molecular weight (HMW) complexes and fragmentation. Size-exclusion chromatography (SEC) analysis revealed that the number of...
متن کامل