Direct Carbon-Carbon Bond Formation from Alcohols and Active Methylenes, Alkoxyketone, or Indoles Catalyzed by Indium Trichloride without Salt Formation
نویسندگان
چکیده
منابع مشابه
Direct coupling of alcohols with alkenylsilanes catalyzed by indium trichloride or bismuth tribromide.
Indium halides or bismuth halides catalyzed the coupling of various alcohols with alkenylsilanes to give the corresponding alkenes stereospecifically without any other activators.
متن کاملNickel-Catalyzed Intramolecular C-O Bond Formation: Synthesis of Cyclic Enol Ethers.
An efficient and exceptionally mild intramolecular nickel-catalyzed carbon-oxygen bond-forming reaction between vinyl halides and primary, secondary, and tertiary alcohols has been achieved. Zinc powder was found to be an essential additive for obtaining high catalyst turnover and yields. This operationally simple method allows direct access to cyclic vinyl ethers in high yields in a single step.
متن کاملPalladium(0)-catalyzed direct cross-coupling reaction of allylic alcohols with aryl- and alkenylboronic acids.
Allylic alcohols can be used directly for the palladium(0)-catalyzed allylation of aryl- and alkenylboronic acids with a wide variety of functional groups. A triphenylphosphine-ligated palladium catalyst turns out to be most effective for the cross-coupling reaction and its low loading (less than 1 mol%) leads to formation of the coupling product in high yield. The Lewis acidity of the organobo...
متن کاملHeterogeneous One-Pot Carbonylation and Mizoroki-Heck Reaction in a Parallel Manner Following the Cleavage of Cinnamaldehyde Derivatives.
Carbon monoxide (CO) and styrene derivatives that can be both generated by a palladium on carbon (Pd/C)-catalyzed carbon-carbon (C-C) bond cleavage reaction of cinnamaldehyde derivatives were effectively utilized in further palladium-catalyzed C-C bond forming reactions in a direct and practical way. CO derived from simple and affordable CO carriers such as cinnamaldehyde or terephthalaldehyde ...
متن کاملDivergent reactivities in fluoronation of allylic alcohols: synthesis of Z-fluoroalkenes via carbon–carbon bond cleavage† †Electronic supplementary information (ESI) available: Full data for the optimization of reaction conditions, detailed experimental procedures, and full characterization of substrates and products. See DOI: 10.1039/c7sc00483d Click here for additional data file.
The incorporation of uorine in pharmaceuticals and agrochemicals has become common practice due to the attractive properties that uorine can provide. Accordingly, uorination chemistry has been extensively explored in the last few decades to deliver uorinated compounds with various substitution patterns. Despite the great progress achieved for catalytic Csp3– F bond formation as well as aryl...
متن کامل