Heterotopic Pancreas in Omphalomesenteric Duct Remnant Results in Persistent Umbilical Discharge

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Umbilical discharge in infancy is a common pediatric problem and usually attributed to infection or an umbilical granulo-ma. However, it is important to investigate if such discharge is due to an underlying congenital abnormality such as umbilical hernia ulceration, urachal remnant, or omphalomesenteric duct remnant, because corrective surgical intervention may then be required. Omphalomesenteric duct remnant can cause umbilical discharge generally through patency between the gut and umbi-licus. However, though rare, umbilical discharge may be due to the presence of heterotopic pancreas. The prevalence of omphalo-mesenteric duct remnant is only 2% of the population, and most of them remain asymptomatic. The present case is an infant with persistent umbilical discharge caused by heterotopic pancreatic tissue in a remnant omphalomesenteric duct. To the best of our knowledge, this is the first such case report in Korea. A 3-month-old female infant presented with persistent umbilical discharge since birth. The infant was born through normal vaginal delivery following an uneventful gestational period and had no congenital anomalies. She had been gaining weight well and had no family history of genitourinary or gastrointesti-nal problems. Ultrasonography of the abdomen revealed an iso-echoic tract posterior to the umbilicus, and the diagnosis of urachal remnant was suspected. On physical examination, small droplets of clear fluid constantly discharged from a normal-looking umbilicus. Laboratory examination results were within normal limits. Under general anesthesia, an incision was made below umbilicus. Surgical exploration showed a fibrous sinus posterior to the umbilicus which was attached to the inner aspect of the umbilicus and the outer wall of the ileum by a fibrous band. Fibrous tissue was excised close to both ends, and the rest was ligated by suture tie. The excised specimen was a 7×6×5-mm-sized whitish fibrous tissue. Histologically, the excised specimen included pancreatic tissue with some small intestinal mucosa and fibrous extracellular components (Fig. 1). Both exocrine and endocrine pancreatic tissues were observed, including acini, ducts, and islets of Langerhans. Acini were separated into lobules by connective tissue. Intercalated ducts were lined by simple low cuboidal epithelium (Fig. 2). The patient was discharged without any postoperative complications and is currently alive without any sequelae. DISCUSSION The omphalomesenteric duct is a long narrow tube that …