ISCR2, another vehicle for bla(VEB) gene acquisition.
نویسندگان
چکیده
The expanded-spectrum beta-lactamase (ESBL) gene bla(VEB-1), identified worldwide in Enterobacteriaceae and Pseudomonas aeruginosa, is associated with either class 1 integrons or repeated elements. We report here the first association of bla(VEB-1a) with the insertion sequence ISCR2 in six Acinetobacter species isolates recovered from Argentina. That genetic structure was likely at the origin of the mobilization of this ESBL gene.
منابع مشابه
A blaVEB-1 variant, blaVEB-6, associated with repeated elements in a complex genetic structure.
bla(VEB-6) was found on the Proteus mirabilis chromosome in a context similar to those of bla(VEB-1a) and bla(VEB-1b), in a truncated gene cassette flanked by 135-bp elements and duplications of the 3'-conserved segment of class 1 integrons. A linked aacA4-aadB-dfrA1-orfC cassette array includes components of Tn1331, illustrating the complex mosaicism of multiresistance regions.
متن کاملDistribution of the bla OXA , bla VEB-1 , and bla GES-1 genes and resistance patterns of ESBL-producing Pseudomonas aeruginosa isolated from hospitals in Tehran and Qazvin, Iran.
INTRODUCTION: Pseudomonas aeruginosa is one of the most common nosocomial pathogens. The emergence of extended spectrum β-lactamases (ESBLs) has been increasingly reported as a major clinical concern worldwide. The main aim of the present study was to determine the distribution of bla OXA, bla PER-1, bla VEB-1, and bla GES-1 genes among ESBL-producing P. aeruginosa isolated from two distinct p...
متن کاملAntimicrobial Resistance Pattern and Their Beta-Lactamase Encoding Genes among Pseudomonas aeruginosa Strains Isolated from Cancer Patients
This study was designed to investigate the prevalence of metallo-β-lactamases (MBL) and extended-spectrum β -lactamases (ESBL) in P. aeruginosa isolates collected from two different hospitals in Cairo, Egypt. Antibiotic susceptibility testing and phenotypic screening for ESBLs and MBLs were performed on 122 P. aeruginosa isolates collected in the period from January 2011 to March 2012. MICs wer...
متن کاملOutbreak of infection caused by Enterobacter cloacae producing the novel VEB-3 beta-lactamase in China.
Over a 4-month period from November 2002 to February 2003, 27 ceftazidime-resistant or cefotaxime-resistant nonrepetitive Enterobacter cloacae isolates were collected from 27 patients hospitalized at HuaShan Hospital, Shanghai, People's Republic of China. The Etest did not detect extended-spectrum beta-lactamases (ESBLs) in those 27 isolates; however, screening by the NCCLS ESBL disk test and c...
متن کاملشناسایی مولکولی ژنهای بتالاکتاماز (PER ،VEB و GES) درسالمونلا انتریتیدیس جدا شده از گوشت طیور با روش Multiplex-PCR
سالمونلوز یک بیماری مهم در انسان و گونههای حیوانات است که بهوسیله سرووارهای مختلف سالمونلاانتریکا ایجاد میشود. سرووار انتریتیدیس یکی از شایعترین سرووارها در انسان و طیور و همچنین عامل بیماری منتقله از طریق غذا میباشد. هدف از این مطالعه بررسی حضور ژنهای blaPER ،blaVEB و blaGES در سویههای سالمونلا انتریتیدی...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 53 11 شماره
صفحات -
تاریخ انتشار 2009