Clinical Experience with Fluorescence Retinal Cinematography.

PHOTOGRAPHY of fluorescence in retinal vessels as described by Novotny and Alvis affords a means of studying the dynamic characteristics of the retinal circulation.' Studies in our laboratory and by other investigators 2 using this method or a modification have demonstrated retinal vascular phenomena that would be difficult to recognize by ophthalmoscopic visualization alone. The single film photographic technic, however, has the disadvantage of allowing exposures at relatively slow speeds. This necessitates multiple injections and grouping arrangements in order to complete a retinal vascular study. In order to evaluate fully the moment-tomoment changes in the retinal circulation during various physiologic and pathologic conditions, a high-speed (up to 16 frames per second) photographic method was developed in our laboratory. This report will describe our observations in 70 patients studied by fluorescence retinal cinematography. The advantages and limitations of the method and the clinical and investigative applications will also be discussed.