Intrinsic novobiocin resistance in Staphylococcus saprophyticus.
نویسندگان
چکیده
Intrinsic novobiocin resistance in Staphylococcus saprophyticus was associated with expression of a novobiocin-resistant form of the drug target protein (GyrB). Site-directed mutagenesis established that resistance depends upon the presence of two specific amino acid residues in GyrB: a glycine at position 85 and a lysine at position 140.
منابع مشابه
Abbreviated scheme for presumptive identification of Staphylococcus saprophyticus from urine cultures.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 51 12 شماره
صفحات -
تاریخ انتشار 2007