Construction of p16Slux, a novel vector for improved bioluminescent labeling of gram-negative bacteria.
نویسندگان
چکیده
A novel vector has been constructed for the constitutive luminescent tagging of gram-negative bacteria by site-specific integration into the 16S locus of the bacterial chromosome. A number of gram-negative pathogens were successfully tagged using this vector, and the system was validated during murine infections of living animals.
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ورودعنوان ژورنال:
- Applied and environmental microbiology
دوره 73 21 شماره
صفحات -
تاریخ انتشار 2007