Title Page Coefficient of Determination Sita Swedish Interactive Threshold Algorithms Swap Short-wavelength-automated-perimetry Va Visual Acuity Wwp White-on-white Perimetry 3

has been peer-reviewed but does not include the final publisher proof-corrections or journal pagination. Citation for the published paper: Bengtsson, B and Heijl, A and Agardh, E "Visual fields correlate better than visual acuity to severity of diabetic retinopathy." Access to the published version may require journal subscription. Title: Visual fields correlate better than visual acuity to severity of diabetic retinopathy Short title: B Bengtsson et al.: Visual fields and visual acuity in diabetic retinopathy Abstract Purpose: To compare outcome of perimetric and visual acuity tests in patients with diabetic retinopathy. Methods: Fifty-nine diabetic patients with different degrees of retinopathy were subjected to stereo fundus photography according to the Early Treatment Diabetic Retinopathy Study (ETDRS), and fluorescein angiography. Conventional White-White-Perimetry (WWP) and Short-Wavelength-Automated-Perimetry (SWAP) were performed and analysed with reference to normal values. Visual acuity (VA) was measured with ETDRS charts. Results: Regression analysis revealed that VA was significantly associated with increasing severity of retinopathy according to the ETDRS scale when VA was estimated by counting LogMar Scores, but not by the conventional reading of the smallest line that could be seen,. VA decreased by 0.02 LogMar/ETDRS step (p=0.03). Degree of visual field loss was significantly associated with increasing severity of retinopathy according to the ETDRS scale, perimetric sensitivity decreasing by 0.44 dB/ETDRS step (p=0.0001) using WWP, and by-0.40 dB/ETDRS step (p=0.04) with SWAP. Area of the foveal avascular zone (FAZ) and adjacent perifoveal intercapillary areas (PIAs) also affected the central visual field as obtained both by WWP, –2.6 dB/ mm 2 (p=0.03), and by SWAP, –7.9dB/ mm 2 (p=0.002), but did not affect VA. The regression model fit for peripheral retinopathy according to the ETDRS scale was better using WWP than SWAP or VA, while SWAP testing was superior to both WWP and VA when measuring effects caused by enlarged FAZ and PIAs. Conclusion: Perimetry can provide more useful information than VA on functional loss in diabetic retinopathy, particularly when the perifoveal capillary network is damaged. Abbrevations: dB decibel ETDRS Early Treatment Diabetic Retinopathy Study FAZ foveal avascular zone Fig. Figure HFA Humphrey Field Analyzer LOCS Lens Opacities Classification System LogMar logarithm of minimum angle of resolution MD Mean Deviation PIA perifoveal intercapillary area r 2