Nicotine increases GABAergic input on rat dorsal raphe serotonergic 1 neurons through alpha 7 nicotinic acetylcholine receptor
نویسنده
چکیده
Nicotine increases GABAergic input on rat dorsal raphe serotonergic 1 neurons through alpha 7 nicotinic acetylcholine receptor 2 3 4 Hernández-Vázquez F, Chavarría K, Garduño J, Hernández-López S and Mihailescu S. 5 6 7 Departamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de 8 México, 04510, México D.F., México 9 10 11 Running head: Nicotine increases the GABAergic input to 5-HT DRN neurons 12 13 14 Corresponding author: Stefan Mihailescu, [email protected] 15 Departamento de Fisiología, Edificio de Investigación A, 5o piso, Facultad de Medicina, 16 Universidad Nacional Autónoma de México, Colonia Copilco-Coyoacan, CP 04510, 17 México DF, México. E-mail:[email protected]. Tel: +52-55-5623-2345 and +52-55-541518 9283. 19 20 21 22 23 Articles in PresS. J Neurophysiol (September 17, 2014). doi:10.1152/jn.00223.2014
منابع مشابه
Nicotine increases GABAergic input on rat dorsal raphe serotonergic neurons through alpha7 nicotinic acetylcholine receptor.
The dorsal raphe nucleus (DRN) contains large populations of serotonergic (5-HT) neurons. This nucleus receives GABAergic inhibitory afferents from many brain areas and from DRN interneurons. Both GABAergic and 5-HT DRN neurons express functional nicotinic acetylcholine receptors (nAChRs). Previous studies have demonstrated that nicotine increases 5-HT release and 5-HT DRN neuron discharge rate...
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