Fibroblast growth factor 23: friend or foe in uremia?

Kant: Friend or Foe of the Believer? Plantinga and Other American Christian Responses to Kant's Epistemology

Parathyroid hormone and phosphorus overload in uremia: impact on cardiovascular system.

BACKGROUND Cardiac remodeling in uremia is characterized by left ventricular hypertrophy, interstitial fibrosis and microvascular disease. Cardiovascular disease is the leading cause of death in uremic patients, but coronary events alone are not the prevalent cause, sudden death and heart failure are. We studied the cardiac remodeling in experimental uremia, evaluating the isolated effect of pa...

Apocrine Metaplasia in Intraductal Papilloma with Foci of DCIS: A Friend or Foe?

Malignant papillary neoplasms of the breast comprise a number of microscopically distinct lesions, where apocrine metaplasia is commonly found in papillomas compared to other papillary lesions including papillary carcinomas. However, association of apocrine metaplasia in papilloma with Ductal Carcinoma in Situ (DCIS) is not very well defined. The lesions with apocrine metaplasia are not only di...

Insulin-like growth factor type 1--friend or foe?

S100/Calgranulin-mediated inflammation accelerates left ventricular hypertrophy and aortic valve sclerosis in chronic kidney disease in a receptor for advanced glycation end products-dependent manner.

OBJECTIVE S100A12 and fibroblast growth factor 23 are biomarkers of cardiovascular morbidity and mortality in patients with chronic kidney disease (CKD). We tested the hypothesis that human S100/calgranulin would accelerate cardiovascular disease in mice subjected to CKD. APPROACH AND RESULTS A bacterial artificial chromosome of the human S100/calgranulin gene cluster containing the genes and...