Spatiotemporal dynamics of pacing in models of anatomical reentry
نویسندگان
چکیده
Reentry around non-conducting ventricular scar tissue, which often causes lethal arrhythmias, is typically treated by rapid stimulation from an implantable defibrillator. However, the mechanisms of termination (success and failure) are poorly understood. To elucidate such mechanisms, we studied pacing of anatomical reentry in 1-D and 2-D excitable cardiac media models. Our results suggest that the existence of inhomogeneity in the reentry circuit is essential for pacing termination of tachycardia to be successful. Considering the role of such inhomogeneities may lead to more effective pacing algorithms.
منابع مشابه
Termination of reentry in an inhomogeneous ring of model cardiac cells.
Reentrant waves propagating in a ring or annulus of excitable media are a model of the basic mechanism underlying a major class of irregular cardiac rhythms known as anatomical reentry. Such reentrant waves are terminated by rapid electrical stimulation (pacing) from an implantable device. Because the mechanisms of such termination are poorly understood, we study pacing of anatomical reentry in...
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Formation of feedback loops of excitation waves (reentrant circuit) around nonconducting ventricular scar tissue is a common cause of lethal cardiac arrhythmias, such as ventricular tachycardia. This is typically treated by rapid stimulation from an implantable device (ICD). However, the mechanisms of reentry termination success and, more importantly, failure, are poorly understood. To study su...
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