Transplantation of Lymphosarcoma in Calves1
نویسندگان
چکیده
Bovine lymphosarcoma cells were transplanted into six new born calves which had first received 200 rads of whole-body irradiation. Distinct subcutaneous masses, involving one or more prefemoral and/or prescapular lymph nodes, were evident within one or two weeks after inoculation of lymphosarcoma cell suspensions. In each instance, it was ]x>ssible to make a histologie diagnosis of lymphosarcoma and, with the exception of one calf in which cytogenetic studies were not attempted, to demonstrate by chromosome analysis that the cells were of donor origin. Whereas some of the transplanted lymphosarcomas regressed following recovery from the effects of irradiation, four of the calves were found to have multiple tumors at autopsy.
منابع مشابه
Studies of marrow transplantation, chemotherapy and cross-circulation in canine lymphosarcoma.
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