Anion-mediated phase transfer of Zinc(II)-coordinated tyrosine derivatives.

نویسندگان

  • Hua Jiang
  • Edward J O'neil
  • Kristy M Divittorio
  • Bradley D Smith
چکیده

[reaction: see text] Tyrosine-derived Zn(2+) coordination complexes and their fluorescent NBD conjugates are synthesized in a short, high-yielding procedure. The Zn(2+) complexes are highly water soluble, but in the presence of sodium laurate they readily transfer into an octanol layer. Furthermore, the NBD-labeled bis-Zn(2+) complex can partition into vesicle membranes containing anionic phospholipids.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

catena-Poly[[μ3-hydroxido-tetra-μ2-pyrid­azine-1:2κ4 N:N′;1:3κ2 N:N′;2:3κ2 N:N′-tetrakis(selenocyanato)-1κN,2κN,3κ2 N-trizinc(II)]-μ-cyanido-1:2′κ2 C:N]

In the crystal structure of the title compound, [Zn(3)(NCSe)(4)(OH)(CN)(C(4)H(4)N(2))(4)](n) one of the two crystallograph-ically independent zinc(II) cations is coordinated by two terminal N-bonded seleno-cyanato anions and two N atoms of two symmetry-related pyridazine ligands in a trigonal-bipyramidal geometry, while the other zinc(II) cation is coordinated by one terminal N-bonded seleno-cy...

متن کامل

Sonochemical synthesis and characterization of nano-sized zinc(II) coordination complex as a precursor for the preparation of pure-phase zinc(II) oxide nanoparticles

In current study, nanoparticles and single crystals of a Zn(II) coordination complex, [Zn(dmph)I2](1), {dmph=2,9-dimethyl-1,10-phenanthroline(neocuproine)}, have been synthesized by the reaction of zinc(II) acetate, KI and neocuproine as ligand in methanol using sonochemical and heat gradient methods, respectively. The nanostructure of 1 was characte...

متن کامل

Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer.

Human carbonic anhydrase II (HCA II) uses a Zn-bound OH(-)/H2O mechanism to catalyze the reversible hydration of CO2. This catalysis also involves a separate proton transfer step, mediated by an ordered solvent network coordinated by hydrophilic residues. One of these residues, Tyr7, was previously shown to be deprotonated in the neutron crystal structure at pH 10. This observation indicated th...

متن کامل

تغییر فاز بلوری کمپلکس نیکل (II) پیریدین-2 و 6-دی‌کربوکسیلات تری هیدرات در دماهای مختلف

A nickel complex with pyridine-2,6-dicarboxylic acid formulated as [Ni(pydcH)2].3H2O was synthesized and its crystal structure determined with single-crystal X-ray at diffraction temperatures (296 K and 120 K).  Pyridine-2,6-dicarboxyli acid  deprotonated on one group of COOH and two pydcH- anion is coordinated to Ni(II) atom as a tridentate ligand forming a distorted octahedral environment. Th...

متن کامل

Bis(4-amino­benzoato)-κ2 O,O′;κO-(2,2′-bipyridine-κ2 N,N′)zinc

In the title complex, [Zn(C(7)H(6)NO(2))(2)(C(10)H(8)N(2))], the Zn(II) cation is coordinated by two amino-benzoate anions and one 2,2'-bipyridine ligand in a distorted trigonal-bipyramidal geometry. The carboxyl-ate group of one aminobenzoate anion coordinates to the Zn(II) cation in a monodentate manner, whereas the carboxyl-ate group of the other amino-benzoate anion chelates the Zn cation w...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Organic letters

دوره 7 14  شماره 

صفحات  -

تاریخ انتشار 2005