Successful treatment of AIDS-related pulmonary Kaposi's sarcoma with liposomal daunorubicin.
نویسندگان
چکیده
We report a 35 year old male, human immunodeficiency virus (HIV)-infected patient with acquired immune deficiency syndrome (AIDS), who presented with rapidly progressive pulmonary Kaposi's sarcoma. The tumour regressed with treatment with liposomal daunorubicin and remained in partial remission until the patient died 12 months later from complications of HIV infection. Liposomal daunorubicin may be a safe and effective alternative to the treatment protocols in current use for pulmonary Kaposi's sarcoma.
منابع مشابه
Pharmacology of liposomal daunorubicin and its use in Kaposi's sarcoma.
In the early 1980s, we first began to see cases of Kaposi's sarcoma (KS) in patients with the lymphadenopathy now known to be associated with infection by the human immunodeficiency virus (HIV). During that period, we were still looking at strong combinations of chemotherapeutic drugs to combat this disease, based on experience in nonimmunosuppressed African patients. It rapidly became apparent...
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Kaposi's sarcoma is a vascular tumor of skin and viscera first described in 1872. Prior to the 1980s, this disease was rarely seen in the Western world, but was quite prevalent in Sub-Saharan African countries. Since the onset of the HIV pandemic in the 1980s, the incidence of Kaposi's sarcoma has increased markedly in Africa and continues to be a significant problem in association with AIDS in...
متن کاملLiposomal daunorubicin as treatment for Kaposi’s sarcoma
Anthracycline compounds including daunorubicin are the foundation of many modem chemotherapeutic regimens. However, the side-effects of these compounds can be severe, leading to alopecia, nausea, immune deficiency, and cardiotoxicity. For immunocompromised patients with aggressive Kaposi's sarcoma (KS), these complications often preclude the completion of appropriate chemotherapeutic regimens. ...
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Fibroepithelial polyps, also named as soft warts, skin tags, or acrochordons, are common benign lesions that may occur on trunk or exterimities. Its association with infectious agents is unclear. Herein, We report a case of extensive fibroepithelial -like polyps on the foot of an AIDS patient following radiotherapy for Kaposi's sarcoma.
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ورودعنوان ژورنال:
- The European respiratory journal
دوره 7 4 شماره
صفحات -
تاریخ انتشار 1994