Restriction site mapping is in separation theory
نویسندگان
چکیده
A computer algorithm for restriction-site mapping consists of a generator of partial maps and a consistency checker. This paper examines consistency checking and argues that a method based on separation theory extracts the maximum amount of information from fragment lengths in digest data. It results in the minimum number of false maps being generated.
منابع مشابه
Modeling of Partial Digest Problem as a Network flows problem
Restriction Site Mapping is one of the interesting tasks in Computational Biology. A DNA strand can be thought of as a string on the letters A, T, C, and G. When a particular restriction enzyme is added to a DNA solution, the DNA is cut at particular restriction sites. The goal of the restriction site mapping is to determine the location of every site for a given enzyme. In partial digest metho...
متن کاملOn $F$-Weak Contraction of Generalized Multivalued Integral Type Mappings with $alpha $-admissible
The purpose of this work is to investigate the existence of fixed points of some mappings in fixed point theory by combining some important concepts which are F-weak contractions, multivalued mappings, integral transformations and α-admissible mappings. In fixed point theory, it is important to find fixed points of some classess under F- or F-weak contractions. Also multivalued mappings is the ...
متن کاملMapper: an intelligent restriction mapping tool
MOTIVATION To determine the most powerful artificial intelligence techniques for automated restriction mapping, and use them to create a powerful multiple-enzyme restriction mapping tool. RESULTS The most effective search engine utilized model-driven exhaustive search and a form of binary logic pruning based on Pratt's separation theory. Additional experimentation led to the development of an...
متن کاملModeling the Network of Municipal Solid Waste Separation Factors using Fuzzy Cognitive Mapping: A Case Study in Tehran
Municipal solid waste management is a major challenge, especially in metropolises. This research focuses on a non-technical issue in municipal solid waste management named municipal solid waste separation at the source and seeks to find the best policy in terms of model results. Source separation for recycling has been recognized as a way to achieve sustainable municipal solid waste (MSW) manag...
متن کاملWebFARM: web server for finite automated restriction mapping
UNLABELLED Restriction endonucleases are indispensable tools in molecular biology and biotechnology. Type II restriction endonucleases are part of restriction modification systems. DNA fragment extraction and restriction mapping are the basis for several biotechnological activities. WebFARM is a server application for identifying restriction endonuclease recognition sites and to give informatio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Computer applications in the biosciences : CABIOS
دوره 4 1 شماره
صفحات -
تاریخ انتشار 1988