Leucocyte migration studies with spleen preparations in Crohn ' s disease ELIZABETH
نویسندگان
چکیده
Thirty-nine patients with Crohn's disease and 17 normal people were tested for hypersensitivity to sarcoid and normal spleen suspensions using the leucocyte migration test. In 26% of the Crohn's cases migration was inhibited, whereas inhibition was not significant in the control group. Migration inhibition did not appear to be related to duration or activity of the disease. Sixty-two percent of the Crohn's patients showed migration stimulation against normal spleen, a phenomenon that did not occur in the control group.
منابع مشابه
Leucocyte migration studies with spleen preparations in Crohn's disease.
Thirty-nine patients with Crohn's disease and 17 normal people were tested for hypersensitivity to sarcoid and normal spleen suspensions using the leucocyte migration test. In 26% of the Crohn's cases migration was inhibited, whereas inhibition was not significant in the control group. Migration inhibition did not appear to be related to duration or activity of the disease. Sixty-two percent of...
متن کاملA study of peripheral leucocyte migration in agarose medium in inflammatory bowel disease.
THE MIGRATION OF PERIPHERAL LEUCOCYTES FROM PATIENTS WITH INFLAMMATORY BOWEL DISEASE WAS INVESTIGATED USING AN AGAROSE PLATE TECHNIQUE AND THREE ANTIGENIC MATERIALS: (1) the enterobacterial common antigen of Kunin; (2) extract from germ-free rat faeces; and (3) Kveim suspension from a sarcoid spleen K19. Inhibition of migration was obtained only with Kunin antigen. It was present in 11 out of 2...
متن کاملLabelled leucocyte scintigraphy in inflammatory bowel disease: clinical applications.
Labelled leucocyte imaging is an established technique for the detection of inflammation and sepsis. Of the many radioisotopes used to label leucocytes, Indiuml1 tropolonate (11 1In) and Technetium-99m hexamethyl propylene amine oxime (99mTc HMPAO) are the most widely used. Leucocytes are obtained from heparinised, peripheral venous blood (40-100 ml) and then separated from erythrocytes and pla...
متن کاملمعرفی یک مورد بیماری کرون
The term “inflammatory” bowel disease” applies to idiopathic, chronic inflammatory bowel disease (IBD): Crohn’s disease and ulcerative colitis. They occur among all age groups but a peak incidence in the second and third decades. Most of IBD occur as ulcerative colitis, but the incidence of Crohn’s disease has risen over the past 20 years. These disorder ar...
متن کاملCrohn’s Disease with Oral Onset - A Case Report
Background: Crohn’s disease is an inflammatory bowel disease that can affect any part of the gastrointestinal (GI) tract including the mouth. Bowel symptoms are predominant. Oral involvement may precede the GI symptoms. This case report presents a patient affected by Crohn’s disease with oral onset. Case presentation: We present a 30-year-old pregnant woman complaining of chronic, ...
متن کامل