COPD: osteoporosis and sarcopenia
نویسندگان
چکیده
Systemic involvement and comorbidities are common in chronic obstructive pulmonary disease (COPD). They add to the burden of disease and are associated with significant disability and mortality. These include cardiovascular disease, mood disorders, anemia, cachexia, skeletal muscle dysfunction and bone pathology. In this article, we review the pathophysiology, diagnosis and treatment of two such comorbidities, osteoporosis and sarcopenia, as they relate to patients with COPD.
منابع مشابه
Presence of sarcopenia in asthma–COPD overlap syndrome may be a risk factor for decreased bone-mineral density, unlike asthma: Korean National Health and Nutrition Examination Survey (KNHANES) IV and V (2008–2011)
BACKGROUND Sarcopenia and decreased bone-mineral density (BMD) are common in elderly people, and are major comorbidities of obstructive airway disease (OAD). However, the relationship between sarcopenia and BMD in each OAD phenotype, especially asthma-COPD overlap syndrome (ACOS), is not yet clear. We aimed to evaluate differences in BMD according to the presence of sarcopenia in each OAD pheno...
متن کاملSarcopenia as an Independent Risk Factor for Decreased BMD in COPD Patients: Korean National Health and Nutrition Examination Surveys IV and V (2008-2011)
BACKGROUND A decrease in bone mineral density (BMD) is a systemic consequence of chronic obstructive pulmonary disease (COPD). Past reports have rarely examined any correlation between sarcopenia and BMD. We investigated the relationship cross-sectionally between the presence of sarcopenia and BMD reduction in COPD patients. METHODS COPD patients aged 50 or older with qualifying spirometry an...
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Objective To investigate the risk factors for osteoporosis in male Taiwanese patients with chronic obstructive pulmonary disease (COPD). Methods This cross-sectional study evaluated male COPD outpatients and age-matched male subjects at a regional teaching hospital. The following data were obtained and analyzed: bone mineral density of the lumbar spine and hip on dual-energy X-ray absorptiome...
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Background & Aim: Osteoporosis is a significant problem in patients with advanced COPD(chronic obstructive pulmonary disease). It is followed by fractures which make life conditions worse for these patients. Several studies demonstrated the relationship between osteoporosis and COPD. This study was designed to determine the prevalence of osteoporosis in male patients with COPD. Patients & M...
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Postmenopausal population is at increased risk of musculoskeletal impairments. Sarcopenia and osteoporosis are associated with significant morbidity and social and health-care costs. These two conditions are uniquely linked with similarities in pathophysiology and diagnostic methods. Uniform diagnostic criteria for sarcopenia are still evolving. Postmenopausal sarcopenia and osteoporosis share ...
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