Deep Insight Section

نویسنده

  • Zehua Wang
چکیده

Ion channels are pore-forming proteins and their function is to facilitate the diffusion of ion across cell membranes by flow of ions down the electrochemical gradient. Voltage-gated ion channels are a class of transmembrane ion channels and are found throughout the body which allowed a rapid and coordinated depolarization in response to voltage change in excitable cells (Catterall, 2010). Recent studies have demonstrated that Voltage-gated ion channels had been found in non-excitable cells. Among these channels, Voltage-gated sodium channels (VGSC) are the new topic and increasing evidences have suggested that which participated in the oncogenic process (Fiske et al., 2006; Mechaly et al., 2005).

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تاریخ انتشار 2012