The 5' untranslated region of alfalfa mosaic virus RNA 1 is involved in negative-strand RNA synthesis.

نویسندگان

  • A Corina Vlot
  • John F Bol
چکیده

The three genomic RNAs of alfalfa mosaic virus each contain a unique 5' untranslated region (5' UTR). Replacement of the 5' UTR of RNA 1 by that of RNA 2 or 3 yielded infectious replicons. The sequence of a putative 5' stem-loop structure in RNA 1 was found to be required for negative-strand RNA synthesis. A similar putative 5' stem-loop structure is present in RNA 2 but not in RNA 3.

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عنوان ژورنال:
  • Journal of virology

دوره 77 20  شماره 

صفحات  -

تاریخ انتشار 2003