A description of genes of Corynebacterium pseudotuberculosis useful in diagnostics and vaccine applications.

Isolation of Corynebacterium pseudotuberculosis from Camel in Iran

Studies on the enhancement of immunity to Corynebacterium pseudotuberculosis.

CAMERON, C. M. & FULS, W. J . P., 1973. Studies on the enhancement of immunity to Corynebacterium pseudotuberculosis. Onderstepoort J. vet. Res. 40 (3), 105-114 (1973). Experiments were undertaken to enhance the immune response of mice, guinea pigs and sheep to C. pseudotuberculosis vaccine. The antibody response of guinea pigs was not increased either by the simultaneous administration of form...

Multilocus Sequencing of Corynebacterium pseudotuberculosis Biotype Ovis Strains

Thirteen Corynebacterium pseudotuberculosis biotype ovis strains isolated from clinical cases of caseous lymphadenitis in Hungary were characterised using multilocus sequencing and their phylogenetic comparison was carried out on the basis of four housekeeping genes (groEL1, infB, dnaK, and leuA). The in silico analysis of the 16 frequently studied housekeeping genes showed that C. pseudotuberc...

An improved Corynebacterium pseudotuberculosis vaccine for sheep.

Extensive experiments in mice confirmed that the immunogenicity of a Corynebacterium pseudotuberculosis vaccine could not be significantly improved with the use of various adjuvants. Immunity against C. pseudotuberculosis likewise could not be enhanced by incorporating various immunostimulants into the vaccine or by the use of live vaccines. However, a combination of aluminium hydroxide gel and...

Efficacy and Toxicity Studies of Oxytetracycline-loaded Calcium Carbonate Nanoparticles in Corynebacterium pseudotuberculosis Infected BALB/C Mice

Background: Caseous Lymphadenitis (CLA) is an important bacterial disease in goats, caused by Corynebacterium pseudotuberculosis. The disease is highly prevalent worldwide and causes significant economic losses to the cattle industry. Currently, the treatment of this disease with antibiotics remains largely unsuccessful due to the nature of the bacteria and the resultant resistance to the drugs...