Laproscopic and open surgical impact in patients treated with Anti aggregant therapy

Background The increase of surgical procedures in older patients requires a standardization in preoperative evaluation and management of patients affected by ischemic cardiopathy under antiplatelet therapy. Methods The sample of 552 patients is represented by the only patients operated on the abdomen and was split in tow groups: Group A (67 patients under home antiaggregant therapy who underwent elective abdominal surgical interventions) and Group B (485 patients not under home antiaggregant therapy who underwent elective abdominal surgical interventions). Group A (antiaggregated patients) was too split in two subgroups: Subgroup A1 (22 patients, who underwent surgical operation with ongoing ASA) and Subgroup A2 (45 patients, who stopped antiaggregant therapy before the operation). Results Global analysis of data shows not significative statistically difference between Major and Minor Surgery Interventions. Statistical comparison of surgical outcomes between Group A and Group B shows differences in prevalence of abdominal collections (6% in Group A vs 0.2% in Group B; p-value 0.0402). In Group A patients who needed transfusions, the average number of Units of Concentrated Erythrocytes was 3.5 (35 U for 10 transfused patients). Statistical comparison of surgical outcomes between Groups A1 and A2 shows not significative statistically difference between them. Conclusion Postoperative bleeding can be more easily managed than thromboembolic complications.