Antifungal Activity of the Essential Oil of Elionurus Muticus (Spreng) Kunth from Zimbabwe against Candida albicans, C. krusei and Cryptococcus neoformans
نویسنده
چکیده
Cultivated Elionurus muticus (Spreng.) Kunth (Gramineae) plant parts were steam distilled for essential oil and evaluated in-vitro for antifungal activity against Candida albicans, C. krusei and Cryptococcus neoformans using agar broth dilution and disc diffusion methods and the activity compared with commercial citral and Cymbopogon citratus DC (Stapf) (lemongrass) oils by measuring the growth inhibition diameter. E. muticus oils showed fungicidal activity with MIC and MFC values between 0.5-10μg/mL. E. muticus whole plant oil showed greater antifungal activity against C. albicans than citral and lemongrass oils. E. muticus whole plant essential oil contains citral and ∆ 1(10) aristolen-2-one as major components, both are known antifungal compounds. Their unique presence in one plant extract could have significant impact in treating mycotic diseases and other opportunistic infections and for use in clinical aromatherapy and in complementary and alternative medicines. Keywords—Elionurus muticus (Spreng) Kunth; essential oil; antifungal activity; Candida spp.; Cryptococcus neoformans
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