Rapid early pregnancy sexing by chorionic villus biopsy and quinacrine staining.

Chorionic villus biopsy was performed in 20 cases scheduled for termination of pregnancy for social reasons, the average gestational age was 8.4 weeks with a range of seven to 11 weeks. The average time taken for the procedure starting from cleaning the vagina to identification of the villi under the dissecting microscope was 12.7 minutes with a range of five to 30 minutes. Chorionic villi material was stained with a 0.25% aqueous solution of quinacrine dihydochloride for five minutes and inspected for 'Y' bodies after mounting in distilled water. For ten chromosomally-confirmed XY cases, the mean 'Y' count was 32.7%:i 12.2%. For ten chromosomally confirmed XX cases, the 'Y' body count was 3.5% i: 2.7%.