A bivalent cationic dye enabling selective photo-inactivation against Gram-negative bacteria.

نویسندگان

  • Ke Li
  • Yang-Yang Zhang
  • Guo-Yu Jiang
  • Yuan-Jun Hou
  • Bao-Wen Zhang
  • Qian-Xiong Zhou
  • Xue-Song Wang
چکیده

A piperazine-modified Crystal Violet was found to be able to selectively inactivate Gram-negative bacteria upon visible light irradiation but left Gram-positive bacteria less damaged, which can serve as a blueprint for the development of novel narrow-spectrum agents to replenish the current arsenal of photodynamic antimicrobial chemotherapy (PACT).

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عنوان ژورنال:
  • Chemical communications

دوره 51 37  شماره 

صفحات  -

تاریخ انتشار 2015