Technosphere Insulin Inhaler – a Review

Inhaled Insulin is a recent therapeutic advance for the treatment of Diabetes. It offers a convenient, as well as accepted, alternative to injected Insulin. Subcutaneous administration of Insulin results in the pain, inconvenience, and disruption of lifestyle associated with the injection of Insulin, so there has been increasing demand in the development of Aerosolized Insulin. Recent studies shown that Aerosolized Insulin is effectively delivered to the alveolar region of the lung, absorption and glucose levels rates are shown similar to those achieved with SC delivered Insulin. Aerosolized Insulin is welltolerated and avoids changes in pulmonary function. Due to some limitations in Aerosolized inhalation, there are novel drug delivery systems of different formulations of Insulin, which are under development, to improve the efficiency of Insulin to deliver into the systemic circulation. Among them Techno sphere Insulin Inhaler offers a viable therapeutic option for the treatment of Diabetes.