Hepatic stellate cells: role in microcirculation and pathophysiology of portal hypertension.
نویسندگان
چکیده
Accumulating evidence suggests that stellate cells are involved in the regulation of the liver microcirculation and portal hypertension. Activated hepatic stellate cells have the necessary machinery to contract or relax in response to a number of vasoactive substances. Because stellate cells play a role in both fibrosis and portal hypertension, they are currently regarded as therapeutic targets to prevent and treat the complications of chronic liver disease.
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ورودعنوان ژورنال:
- Gut
دوره 50 4 شماره
صفحات -
تاریخ انتشار 2002