The cognitive phenotype of spina bifida meningomyelocele.

A model of neurocognitive function in spina bifida over the life span.

Spina bifida myelomeningocele (SBM), a neural tube defect that is the product of a complex pattern of gene-environment interactions, is associated with naturally occurring, systematic variability in the neural phenotype and in environmental factors that lead to systematic variability in the cognitive phenotype. We characterize the basis for variability in the cognitive phenotype of children wit...

Bacterial Meningitis in Spina Bifida Cystica

Meningitis is a well-known complication of meningomyelocele, but the problems of its diagnosis and treatment have so far received scant attention. Some children with meningomyelocele have a small neurological deficit and no hydrocephalus. Others with hydrocephalus may benefit from modern treatment and grow up to lead normal lives. The problem of meningitis in meningomyelocele is, therefore, wor...

Associations of ethnicity and SES with IQ and achievement in spina bifida meningomyelocele.

OBJECTIVES We evaluated whether the phenotypic pattern of higher verbal than nonverbal IQ in children with spina bifida meningomyelocele (SBM) is consistent across subgroups differing in ethnicity and SES. We also explored the relation of cognitive and academic performance. METHODS Non-Hispanic White (n = 153) and Hispanic (n = 80) children with SBM received the Stanford Binet Test of Intelli...

Spina Bifida (Myelomeningocele)

Neurosurgical management of myelomeningocele (spina bifida).