1 Viral load of high - risk human papillomaviruses as reliable clinical predictor for the presence of 1 cervical lesions 2 3 Running title : High viral load identifies cervical lesions 4 5
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چکیده
Viral load of high-risk human papillomaviruses as reliable clinical predictor for the presence of 1 cervical lesions 2 3 Running title: High viral load identifies cervical lesions 4 5 Authors: 6 Markus Schmitt, Christophe Depuydt, Ina Benoy2, Johannes Bogers2, Jerome Antoine, Michael 7 Pawlita, and Marc Arbyn on behalf of the VALGENT study group 8 9 1 Department Genome Modifications and Carcinogenesis (F020) 10 Research Program Infection and Cancer 11 German Cancer Research Center (DKFZ) 12 Im Neuenheimer Feld 242 13 69120 Heidelberg 14 Germany 15 16 2 Labo Lokeren campus Riatol, Department of Molecular Diagnostics 17 Sonic Healthcare Benelux 18 Emiel Vloorsstraat 9, 2020 Antwerp 19 Belgium 20 21 3 Unit of Cancer Epidemiology 22 Scientific Institute of Public Health 23 Juliette Wytsmanstreet 14 24 1050 Brussels 25 Belgium 26 27 * To whom correspondence should be addressed: E-mail: [email protected] 28
منابع مشابه
presence of 1 cervical lesions 2 3 Running title : High viral load identifies cervical lesions 4 5
Viral load of high-risk human papillomaviruses as reliable clinical predictor for the presence of 1 cervical lesions 2 3 Running title: High viral load identifies cervical lesions 4 5 Authors: 6 Markus Schmitt, Christophe Depuydt, Ina Benoy2, Johannes Bogers2, Jerome Antoine, Michael 7 Pawlita, and Marc Arbyn on behalf of the VALGENT study group 8 9 1 Department Genome Modifications and Carcino...
متن کاملViral load of high-risk human papillomaviruses as reliable clinical predictor for the presence of cervical lesions.
BACKGROUND Infections with high-risk human papillomaviruses (Hr-HPV) can cause malignant transformation of the human cervical epithelium. HPV DNA tests generally are very sensitive to detect cervical neoplastic lesions but also identify transient HPV infections. As a consequence, the specificity and positive predictive value are low. METHODS We analyzed viral load of Hr- and possibly Hr-HPV t...
متن کاملMultiple human papillomavirus infections with high viral loads are associated with cervical lesions but do not differentiate grades of cervical abnormalities.
Multiple human papillomavirus (HPV) genotypes often coexist within cervical epithelia and are frequently detected together in smears of different grades of cervical neoplasia. Describing the association between multiple infections and cervical disease is important in generating hypotheses regarding its pathogenesis. We analyzed the prevalence of multiple HPV infections and their attribution to ...
متن کاملViral DNA load of high-risk human papilloma virus is closely associated with the grade of cervical lesions.
This study is to explore the correlation between the viral load of high-risk human papilloma virus (HPV) and the degree of cervical lesions, as well as the follow-up monitoring role of high-risk HPV measurements in the treatment of patients with cervical lesions. Hybrid capture-2 method was used to measure the amount of high-risk HPV load of 361 patients who were enrolled from January 2009 to D...
متن کاملDetection and estimation of human papillomavirus viral load in patients with cervical lesions.
Human papillomavirus (HPV) high risk genotype infection and HPV viral load influences the development of invasive cervical cancer and cervical intra-epithelial neoplasia (CIN). HPV DNA testing for screening of cervical cancers may play a potential role in its early detection and management. The present study detected HPV DNA and estimated HPV viral load in different types of cervical lesions am...
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