fibrinolysis in women with heavy menstrual bleeding

نویسندگان

  • Sophie Wiewel-Verschueren
  • H. Marieke Knol
  • Ton Lisman
  • Dick H. Bogchelman
  • Hanneke C. Kluin-Nelemans
  • Ate G.J. van der Zee
  • André B. Mulder
  • Karina Meijer
چکیده

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منابع مشابه

Increased Plasma Clot Permeability and Susceptibility to Lysis Are Associated with Heavy Menstrual Bleeding of Unknown Cause: A Case-Control Study

BACKGROUND Formation of compact and poorly lysable clots has been reported in thromboembolic disorders. Little is known about clot properties in bleeding disorders. OBJECTIVES We hypothesized that more permeable and lysis-sensitive fibrin clots can be detected in women with heavy menstrual bleeding (HMB). METHODS We studied 52 women with HMB of unknown cause and 52 age-matched control women...

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Clinical Medicine Insights: Women’s Health

Menorrhagia or Heavy Menstrual Bleeding (HMB) remains a public health challenge among women in the reproductive age group. Anti-fibrinolytics such as tranexamic acid and epsilon aminocaproic acid, play an important role in the medical management of HMB, as HMB is associated with an increase in local fibrinolysis. Lysteda is a novel oral formulation of tranexamic acid which has recently been app...

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The spontaneous resolution of heavy menstrual bleeding in the perimenopausal years

OBJECTIVE To obtain estimates of the rate of spontaneous resolution of heavy menstrual bleeding and to explore any association with specific menstrual symptoms. DESIGN Two-year prospective cohort study. SETTING Seven general practices, with 67 100 registered patients. POPULATION All women aged 40-54 years on the practices age-sex registers. METHODS Baseline postal questionnaire, with fo...

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P-45: Randomized Clinical Trial of Medroxyprogestrone Acetate and Tranexamic Acid in Women with Menorrhagia

Background: Heavy menstrual bleeding is a leading cause of poor quality of life and iron deficiency anemia in reproductive aged women. The aim of this study was to compare the efficacy and acceptability of Medroxyprogestrone acetate and Tranexamic acid in menorrhagia management. Materials and Methods: Inclusion criteria were: age 20-45 years, regular menses, not using hormonal drugs for previou...

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Menstrual bleeding patterns: A community-based cross-sectional study among women aged 18-45 years in Southern Brazil

BACKGROUND Population variation in the duration and amount of menstrual bleeding has received little attention in the literature. This study describes these characteristics and investigates the distribution of self-perceived amount of menstrual bleeding according to socio-demographic, behavioral, and reproductive characteristics. METHODS A community-based cross-sectional study was conducted a...

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تاریخ انتشار 2017