Stability of bacitracin methylene disalicylate
نویسندگان
چکیده
A study was carried out to determine if the presence of bacitracin methylene disalicylate (BMD) interfered with the assay of chlortetracycline (CTC) and if the presence of CTC interfered with the assay of BMD when both are combined in a pig feed. In addition, the potential influence of steam pelleting on active concentrations of BMD and CTC was determined. Further, the stability of BMD in the presence of CTC and the stability of CTC in the presence of BMD was determined in pelleted pig feed. Finally, the homogeneity of BMD and CTC during normal mixing procedures and the extent of segregation during shipping were determined. The results of the study demonstrated that when present in pig feeds at levels anticipated for actual use, BMD and CTC can be assayed without interference, that each of these antibiotics remains within specifications for up to 13 weeks of storage and that standard feed mixing results in homogenous dispersion of the antibiotics which remain dispersed following transport. # 1999 Elsevier Science B.V. All rights reserved.
منابع مشابه
Antibiotic treatment of ulcerative enteritis of bobwhite quail.
Penicillin-streptomycin, bacitracin methylene disalicylate, zinc bacitracinm, soluble bacitracin methylene disalicylate, streptomycin (25%) and spectinomycin were used as prophylactic and therapeutic treatments for ulcerative enteritis in bobwhite quail (Colinus virginianus). Penicillin-streptomycin was the most effective prophylactic and streptomycin (25%) was the most effective therapeutic ag...
متن کاملFactors associated with death due to hemorrhagic bowel syndrome in two large commercial swine farms
Results: Gender, animal density, and concurrent disease were not associated with death due to HBS. Rates of death due to HBS were higher for pigs finished during the summer than for those finished in the winter. Rates of death due to HBS were lower in pigs fed rations containing bacitracin methylene disalicylate or chlortetracycline than in pigs on rations containing virginiamycin or no antibio...
متن کاملEffectiveness of Phytogenic Feed Additive as Alternative to Bacitracin Methylene Disalicylate on Hematological Parameters, Intestinal Histomorphology and Microbial Population and Production Performance of Japanese Quails
This study was conducted to evaluate the effects of phytogenic additive and antibiotic growth promoter in laying Japanese quails. One hundred and sixty five quails were divided into three groups of 5 replicates and 11 quails (8 females and 3 males) in each replicate. Treatment 1 was fed control diet, treatment 2 was fed control diet supplemented with 0.05% bacitracin methylene disalicylate as a...
متن کاملThe efficacy of bacitracin methylene disalicylate when fed in combination with narasin in the management of necrotic enteritis in broiler chickens.
The efficacy of bacitracin methylene disalicylate (BMD) in the management of necrotic enteritis (NE) when fed in combination with narasin was investigated in a floor-pen study of 2,000 broiler chickens using a Clostridium perfringens inoculum challenge model. Treatments consisted of 1) nonchallenged-nonmedicated; 2) challenged-nonmedicated; 3) challenged-narasin (70 ppm); 4) challenged-BMD (55 ...
متن کاملComparative Efficacy of an Organic Acid Blend and Bacitracin Methylene Disalicylate as Growth Promoters in Broiler Chickens: Effects on Performance, Gut Histology, and Small Intestinal Milieu
This study evaluated the efficacy of organic acids as a growth promoter for broiler chickens relative to antibiotic growth promoters (AGPs). Broiler chickens were supplemented with graded doses of an organic acid blend (OAB, 1 g and 2 g/kg diet) and bacitracin methylene disalicylate (BMD, 0.5 g and 1 g/kg diet) for 35 days. Supplementation of OAB improved (P < .001) feed conversion ratio (FCR) ...
متن کامل