Pathophysiology and Biomechanics of the Aging Spine

نویسندگان

  • Michael Papadakis
  • Georgios Sapkas
  • Elias C Papadopoulos
  • Pavlos Katonis
چکیده

AGING OF THE SPINE IS CHARACTERIZED BY TWO PARALLEL BUT INDEPENDENT PROCESSES: the reduction of bone mineral density and the development of degenerative changes. The combination of degeneration and bone mass reduction contribute, to a different degree, to the development of a variety of lesions. This results in a number of painful and often debilitating disorders. The present review constitutes a synopsis of the pathophysiological processes that take place in the aging spine as well as of the consequences these changes have on the biomechanics of the spine. The authors hope to present a thorough yet brief overview of the process of aging of the human spine.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cervical spondylosis anatomy: pathophysiology and biomechanics.

Cervical spondylosis is the most common progressive disorder in the aging cervical spine. It results from the process of degeneration of the intervertebral discs and facet joints of the cervical spine. Biomechanically, the disc and the facets are the connecting structures between the vertebrae for the transmission of external forces. They also facilitate cervical spine mobility. Symptoms relate...

متن کامل

Pathophysiology of lumbar disc degeneration: a review of the literature.

Lumbar disc degeneration occurs because of a variety of factors and results in a multitude of conditions. Alterations in the vertebral endplate cause loss of disc nutrition and disc degeneration. Aging, apoptosis, abnormalities in collagen, vascular ingrowth, loads placed on the disc, and abnormal proteoglycan all contribute to disc degeneration. Some forms of disc degeneration lead to loss of ...

متن کامل

Stress Analysis of the Human Ligamentous Lumber Spine-From Computer-Assisted Tomography to Finite Element Analysis

Detailed investigation on biomechanics of a complex structure such as the human lumbar spine requires the use of advanced computer-based technique for both the geometrical reconstruction and the stress analysis. In the present study, the computer-assisted tomography (CAT) and finite element method (FEM) are merged to perform detailed three dimensional nonlinear analysis of the human ligamentous...

متن کامل

Finite element study of healthy, pathological and surgical lumbar spine biomechanics

Lumbar pain is one of the most common problems of population. Far too often it is caused by ageing and degeneration of intervertebral discs (IVD). Fusion techniques, as arthrodesis, were the first surgeries used to avoid lumbar pathologies. However, arthrodesis reduced dramatically the spine movement. So the aim of this work was to study numerically how different pathologies affect lumbar spine...

متن کامل

Spine Biomechanics: A Review of Current Approaches

The lumbar spine is a fundamental structure of the human body involved in almost any functional activity. Thus, the investigation of spine pathophysiology is of relevance for many research fields. In particular, research on spine biomechanics may provide important insights on the etiology of diseases affecting spinal tissues. More specifically, spine mechanics and biochemistry can provide cruci...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2011