AT2433-A1, AT2433-A2, AT2433-B1 and AT2433-B2 novel antitumor compounds produced by Actinomadura melliaura. II. Structure determination.
نویسندگان
چکیده
The chemical structures of AT2433-A1 (2), AT2433-A2 (3), AT2433-B1 (4) and AT2433-B2 (5) were elucidated by degradation and spectroscopic studies. Compounds 2-5 are disaccharides closely related to rebeccamycin. The aglycone in 2 and 3 was determined to be 6-N-methyl-11-chloro-5H-indolo[2,3-a]pyrolo[3,4-c]carbazole and in 4 and 5 it was determined to be 6-N-methyl-5H-indolo[2,3-a]pyrolo[3,4-c]carbazole. Compounds 2 and 4 are 4-N"-methyl analogs of 3 and 5.
منابع مشابه
AT2433-A1, AT2433-A2, AT2433-B1, and AT2433-B2 novel antitumor antibiotic compounds produced by Actinomadura melliaura. Taxonomy, fermentation, isolation and biological properties.
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ورودعنوان ژورنال:
- The Journal of antibiotics
دوره 42 12 شماره
صفحات -
تاریخ انتشار 1989