Molecular mimicry. Cross-reactivity between microbes and host proteins as a cause of autoimmunity.
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منابع مشابه
Immune evasion and the evolution of molecular mimicry in parasites.
Parasites that are molecular mimics express proteins which resemble host proteins. This resemblance facilitates immune evasion because the immune molecules with the specificity to react with the parasite also cross-react with the host's own proteins, and these lymphocytes are rare. Given this advantage, why are not most parasites molecular mimics? Here we explore potential factors that can sele...
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303 Rev Bras Reumatol 2012;52(3):303-306 Molecular mimicry has been proposed as a pathogenic mechanism for autoimmune disease. The hypothesis is based on the epidemiological, clinical, and experimental studies and in evidence fi nding an association between infectious agents and autoimmune disease, observing cross-reactivity of immune agents with host antigens and microbial determinants.1 Recen...
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ورودعنوان ژورنال:
- Current topics in microbiology and immunology
دوره 145 شماره
صفحات -
تاریخ انتشار 1989