Thromboangiitis obliterans.

نویسندگان

I J Schatz

G Fine

W R Eyler

چکیده

Thromboangiitis obliterans (TAO) has been a recognized clinical entity for more than half a century (Buerger, 1908). Distal arterial occlusive disease and/or recurrent superficial thrombophlebitis occurring in an adult male smoker, in the absence of known cause, constitutes a distinctive and unmistakable syndrome (Brown, Allen, and Mahorner, 1928). However, the existence of this disorder has been questioned because it was not being encountered clinically, and meticulous examination of unselected amputated limbs did not reveal the characteristic microscopical changes (Wessler et al., 1960). For these reasons, it was suggested that the diagnostic category of thromboangiitis obliterans be discarded (Wessler, 1961). If the question of the existence of this disorder had no practical importance, arguments about it could be regarded as exercises in medical pedantry and be dismissed. We feel, however, that this syndrome is separate and distinct, and that failure to recognize it will deprive patients of correct advice and proper treatment. In our opinion, the lack of plentiful characteristic histological changes and the failure to detect such cases clinically are not sufficient arguments to deny what is a clear clinical syndrome. This study was undertaken to emphasize the clinical, radiographic, histological, and prognostic features of Buerger's disease and the differences from other forms of vascular disease.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Molecular mechanisms regulating immune responses in thromboangiitis obliterans: a comprehensive review

Thromboangiitis obliterans (TAO) is a thrombotic-occlusive as well as an inflammatory peripheral vascular disease with unknown etiology. Recent evidence has supported the immunopathogenesis of the disease, however, the factors contributing to the altered immune function and vascular tissue inflammation are still unclear. This review was intended to collate the more current knowledge on the regu...

متن کامل

The Incidence and Prevalence of Thromboangiitis Obliterans in Taiwan: A Nationwide, Population-based Analysis of Data Collected from 2002 to 2011

OBJECTIVE To estimate the incidence and prevalence of thromboangiitis obliterans in Taiwan in the period spanning from 2002 to 2011. METHODS We identified all incident and prevalent cases with a diagnosis of thromboangiitis obliterans (International Classification of Diseases, Ninth Revision code 443.1) in the period spanning from 2002 to 2011 using Taiwan's National Health Insurance Research...

متن کامل

Recurrent Vitreous Haemorrhage Associated with Thromboangiitis Obliterans.

THROMBOANGIITIS obliterans has been considered to be a disease of the blood vessels which usually affects the vessels of the limbs. It has been established, however, that it can affect any of the blood vessels in the body, including those which supply the brain and the retina. This is the report of a case which presented with vitreous haemorrhage, and in which the diagnosis of thromboangiitis o...

متن کامل

End stage renal disease caused by thromboangiitis obliterans: a case report

INTRODUCTION Thromboangiitis obliterans or Buerger's disease is a nonatherosclerotic, segmental, inflammatory vasculitis that is strongly associated with tobacco products and commonly affects the small- and medium-sized arteries of the upper and lower extremities. However, the disease can, rarely, involve large central or visceral arteries. We report here the case of end stage renal disease due...

متن کامل